Journal article

The activity and connectivity of the facial emotion processing neural circuitry in bipolar disorder: a systematic review

Lisa S Furlong, Susan L Rossell, Georgia F Caruana, Vanessa L Cropley, Matthew Hughes, Tamsyn E Van Rheenen

JOURNAL OF AFFECTIVE DISORDERS | ELSEVIER | Published : 2021

Abstract

BACKGROUND: Facial emotion processing abnormalities may be a trait feature of bipolar disorder (BD). These social cognitive impairments may be due to alterations in the neural processing of facial affective information in visual ("core"), and limbic and prefrontal ("extended") networks, however, the precise neurobiological mechanism(s) underlying these symptoms are unclear. METHODS: We conducted a systematic review to appraise the literature on the activity and connectivity of the facial emotion processing neural circuitry in BD. Two reviewers undertook a search of the electronic databases PubMed, Scopus and PsycINFO, to identify relevant literature published since inception up until Septemb..

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Grants

Awarded by National Health and Medical Research Council


Funding Acknowledgements

This work was supported by the National Health and Medical Research Council [grant numbers 1088785, 1154651, 1177370]; the National Imaging Facility; the Fay Marles Scholarship Fund; Australian Rotary Health; the Ian Parker Bipolar Research Fund; Brunslea Park Estate and; the University of Melbourne. The authors acknowledge the facilities and scientific assistance of the National Imaging Facility, a National Collaborative Research Infrastructure Strategy (NCRIS) capability, at the Swinburne Neuroimaging Facility, Swinburne University of Technology.