Determinants of Cardiovascular Risk in 7000 Youth with Type 1 Diabetes in the Australasian Diabetes Data Network

JJ Couper; TW Jones; M Chee; HL Barrett; P Bergman; F Cameron; ME Craig; P Colman; EE Davis; KC Donaghue; PG Fegan; PS Hamblin; DJ Holmes-Walker; C Jefferies; S Johnson; MT Mok; BR King; R Sinnott; G Ward; BJ Wheeler; A Zimmermann; A Earnest

Journal article

Determinants of Cardiovascular Risk in 7000 Youth with Type 1 Diabetes in the Australasian Diabetes Data Network

JJ Couper, TW Jones, M Chee, HL Barrett, P Bergman, F Cameron, ME Craig, P Colman, EE Davis, KC Donaghue, PG Fegan, PS Hamblin, DJ Holmes-Walker, C Jefferies, S Johnson, MT Mok, BR King, R Sinnott, G Ward, BJ Wheeler Show all

Journal of Clinical Endocrinology and Metabolism | ENDOCRINE SOC | Published : 2021

DOI: 10.1210/clinem/dgaa727

Abstract

Context: Cardiovascular disease occurs prematurely in type 1 diabetes. The additional risk of overweight is not well characterized. Objective: The primary aim was to measure the impact of body mass index (BMI) in youth with type 1 diabetes on cardiovascular risk factors. The secondary aim was to identify other determinants of cardiovascular risk. Design: Observational longitudinal study of 7061 youth with type 1 diabetes followed for median 7.3 (interquartile range [IQR] 4-11) years over 41 (IQR 29-56) visits until March 2019. Setting: 15 tertiary care diabetes centers in the Australasian Diabetes Data Network. Participants were aged 2 to 25 years at baseline, with at least 2 measurements of..

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University of Melbourne Researchers

Fergus Cameron Author

Peter Colman Author

Peter Hamblin Author

Meng Tuck Mok Author

Grants

Funding Acknowledgements

This research was conducted as part of the Australasian Diabetes Data Network. We are grateful to JDRF Australia, the Australian Research Council, and to the children and young people with diabetes and their families who provided the data. We acknowledge the work of Dr Loren Bruns, Senior Software Developer, Melbourne eResearch Group, the University of Melbourne. This research was supported by JDRF Australia, the recipient of the Australian Research Council Special Research Initiative in Type 1 Juvenile Diabetes and the Channel 7 Research Foundation of South Australia. Dr. Jenny Couper and Dr. Arul Earnest are the guarantors of this work and, as such, had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. There is no conflict of interest nor disclosure for any author.