Journal article

Breast Cancer Chemoprevention: Use and Views of Australian Women and Their Clinicians

Courtney Macdonald, Christobel M Saunders, Louise A Keogh, Morgan Hunter, Danielle Mazza, Sue-Anne Mclachlan, Sandra C Jones, Stephanie Nesci, Michael L Friedlander, John L Hopper, Jon D Emery, Martha Hickey, Roger L Milne, Kelly-Anne Phillips

Cancer Prevention Research | AMER ASSOC CANCER RESEARCH | Published : 2021

Abstract

Guidelines endorse the use of chemoprevention for breast cancer risk reduction. This study examined the barriers and facilitators to chemoprevention use for Australian women at increased risk of breast cancer, and their clinicians. Surveys, based on the Theoretical Domains Framework, were mailed to 1,113 women at ≥16% lifetime risk of breast cancer who were enrolled in the Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer cohort study (kConFab), and their 524 treating clinicians. Seven hundred twenty-five women (65%) and 221 (42%) clinicians responded. Only 10 (1.4%) kConFab women had ever taken chemoprevention. Three hundred seventy-eight (52%) kConFab women,..

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Grants

Awarded by Cancer Australia


Awarded by National Breast Cancer Foundation (PdCCRS)


Awarded by Australian National Breast Cancer Foundation


Awarded by Australian National Health and Medical Research Council


Awarded by National Institute of Health USA


Funding Acknowledgements

Wethank Sandra Picken, Lucy Stanhope, Sarah O'Connor, Gerda Evans, Leslie Gilham, Heather Thorne, Eveline Niedermayr, Sharon Guo, the kConFab research nurses and the heads and staff of the Family Cancer Clinics. We thank the women, their families, and the clinicians that participated in this research. This research was supported by Cancer Australia and the National Breast Cancer Foundation (PdCCRS #1100868). kConFab and the kConFab Follow-Up Study have received additional funding support from Cancer Australia (809195), the Australian National Breast Cancer Foundation (IF 17), the Australian National Health and Medical Research Council (454508, 288704, and 145684), the National Institute of Health USA (1RO1CA159868), the Queensland Cancer Fund, the Cancer Councils of New South Wales, Victoria, Tasmania and South Australia, and the Cancer Foundation of Western Australia. K.-A. Phillips is an Australian National Breast Cancer Foundation Fellow (PRAC17-004). The contents of this manuscript are solely the responsibility of the authors and do not necessarily reflect the views of Cancer Australia.