Journal article
Inspector: a lysine succinylation predictor based on edited nearest-neighbor undersampling and adaptive synthetic oversampling
Y Zhu, C Jia, F Li, J Song
Analytical Biochemistry | ACADEMIC PRESS INC ELSEVIER SCIENCE | Published : 2020
Abstract
Lysine succinylation is an important type of protein post-translational modification and plays a key role in regulating protein function and structural changes. The mechanism and function of succinylation have not been clarified. The key to better understanding the precise mechanism and functional role of succinylation is the identification of lysine succinylation sites. However, conventional experimental methods for succinylation identification are often expensive, time-consuming, and labor-intensive. Therefore, the new development of computational approaches to effectively identify lysine succinylation sites from sequence data is much needed. In this study, we proposed a novel predictor fo..
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Awarded by National Institutes of Health
Funding Acknowledgements
This work was supported by Fundamental Research Funds for the Central Universities (3132019175, 3132019323, 3132018280), the National Natural Science Foundation of Liaoning Province (20180550307, 20170540092) and the Natural Science Foundation of China (61803065). J.S. and F.L.' works were supported by grants from the National Health and Medical Research Council of Australia (NHMRC) (APP490989, APP1127948 and APP1144652), the Australian Research Council (ARC) (LP110200333 and DP120104460), the National Institute of Allergy and Infectious Diseases of the National Institutes of Health (R01 AI111965), and a Major Inter-Disciplinary Research (IDR) project awarded by Monash University.