Journal article

Acceptability, motivation and the prospect of cure for people living with HIV and their healthcare providers in HIV cure-focused treatment interruption studies

Jillian SY Lau, Miranda Z Smith, Brent Allan, Cipriano Martinez, Jennifer Power, Sharon R Lewin, James H McMahon

AIDS Research and Therapy | BMC | Published : 2020

Abstract

BACKGROUND: Analytical treatment interruptions (ATI) are commonly used clinical endpoints to assess interventions aimed at curing HIV or achieving antiretroviral therapy (ART)-free HIV remission. Understanding the acceptability of ATI amongst people living with HIV (PLHIV) and their HIV healthcare providers (HHP) is limited. METHODS: Two online surveys for PLHIV and HHP assessed awareness and acceptability of ATI, and understanding of the prospect for HIV cure in the future. Responses were collected from July 2017-January 2018. A descriptive analysis was performed and similar questions across the two surveys were compared using χ squared test. RESULTS: 442 PLHIV and 144 HHP completed the sur..

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Grants

Awarded by NHMRC Postgraduate Scholarship


Awarded by NHMRC Early Career Fellowship


Awarded by National Institutes of Health Delaney AIDS Research Enterprise


Awarded by American Foundation for AIDS Research


Awarded by NHMRC


Funding Acknowledgements

The institution of JHM and JSYL receive funding from Gilead Sciences, Viiv Healthcare, Merck and Shire to conduct clinical trials. JSYL has an NHMRC Postgraduate Scholarship (1151607). JHM has an NHMRC Early Career Fellowship (1111099). SRL is an NHMRC Practitioner Fellow (1042654) and is supported by the National Institutes of Health Delaney AIDS Research Enterprise (UM1 AI126611-01) and the American Foundation for AIDS Research (109226-58 RGRL). The listed funding bodies played no role in the design of the study and collection, analysis, and interpretation of data, or in the writing of this manuscript.