Journal article

Multiple lifestyle factors and depressed mood: a cross-sectional and longitudinal analysis of the UK Biobank (N=84,860)

Jerome Sarris, Russell Thomson, Fiona Hargraves, Melissa Eaton, Michael de Manincor, Nicola Veronese, Marco Solmi, Brendon Stubbs, Alison R Yung, Joseph Firth

BMC MEDICINE | BMC | Published : 2020


BACKGROUND: There is now evolving data exploring the relationship between depression and various individual lifestyle factors such as diet, physical activity, sleep, alcohol intake, and tobacco smoking. While this data is compelling, there is a paucity of longitudinal research examining how multiple lifestyle factors relate to depressed mood, and how these relations may differ in individuals with major depressive disorder (MDD) and those without a depressive disorder, as 'healthy controls' (HC). METHODS: To this end, we assessed the relationships between 6 key lifestyle factors (measured via self-report) and depressed mood (measured via a relevant item from the Patient Health Questionnaire) ..

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Awarded by NHMRC

Awarded by University of Manchester Presidential Fellowship

Awarded by UK Research and Innovation Future Leaders Fellowship

Awarded by Health Education England (HEE)

Awarded by National Institute for Health Research (NIHR)

Funding Acknowledgements

We would firstly like to thank the participants and staff of the UK Biobank for making this research possible. JS is supported by an NHMRC Clinical Research Fellowship APP1125000. JF is supported by a University of Manchester Presidential Fellowship (P123958) and a UK Research and Innovation Future Leaders Fellowship (MR/T021780/1) and has received support from a NICM-Blackmores Institute Fellowship. This research has been conducted using the UK Biobank Resource under Application Number 22125. BS is supported by a Clinical Lectureship (ICA-CL-2017-03-001) jointly funded by Health Education England (HEE) and the National Institute for Health Research (NIHR); he received funding from the NIHR Biomedical Research Centre at South London and the Maudsley NHS Foundation Trust. BS is also supported by the Maudsley Charity, King's College London and the NIHR South London Collaboration for Leadership in Applied Health Research and Care (CLAHRC). This paper presents independent research. The views expressed in this publication are those of the authors and not necessarily those of the acknowledged institutions. ARY is supported by an NHMRC Principal Research Fellowship.