The effect of concomitant benzodiazepine use on neurocognition in stable, long-term patients with bipolar disorder
Yolanda Canada, Ana Sabater, Pilar Sierra, Vicent Balanza-Martinez, Michael Berk, Seetal Dodd, Pablo Navalon, Lorenzo Livianos, Ana Garcia-Blanco
AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY | SAGE PUBLICATIONS LTD | Published : 2020
OBJECTIVE: Neurocognitive dysfunction is a common feature of bipolar disorder even in euthymia, and psychopharmacological treatment could have an effect on cognition. Long-term prescription of benzodiazepines in bipolar disorder is a common practice, and their effect on neurocognition has not been well studied in this population. The aim of this study was to evaluate the impact of concomitant benzodiazepine long-term use on neurocognitive function in stable euthymic bipolar disorder patients. METHODS: Seventy-three euthymic bipolar disorder outpatients and 40 healthy individuals were assessed using a neurocognitive battery. Patients were classified in two groups according to the presence of ..View full abstract
Awarded by Carlos III Health Institute
Awarded by Carlos III Health Institute (Spanish Ministry of Economy and Innovation) `Rio Hortega' fellowship
Awarded by National Health and Medical Research Council (NHMRC) Senior Principal Research Fellowships
The author(s) disclosed receipt of the following financial support for the research, authorship and/or publication of this article: V.B.-M. is supported by the national grant (PI16/01770) from the Carlos III Health Institute. P.N. is supported by a Carlos III Health Institute (Spanish Ministry of Economy and Innovation) `Rio Hortega' fellowship (CM19/00078). M.B. is supported by National Health and Medical Research Council (NHMRC) Senior Principal Research Fellowships (APP1059660 and APP1156072). A.G.-B. acknowledges a FIS Project (PI18/01352) and 'Juan Rodes' grant (JR17/00003) from the Carlos III Health Institute and cofinanced by the European Development Regional Fund 'A way to achieve Europe'.