Treating male partners of women with bacterial vaginosis (StepUp): a protocol for a randomised controlled trial to assess the clinical effectiveness of male partner treatment for reducing the risk of BV recurrence
Lenka A Vodstrcil, Erica L Plummer, Michelle Doyle, Christopher K Fairley, Colette McGuiness, Deborah Bateson, Jane S Hocking, Matthew G Law, Kathy Petoumenos, Basil Donovan, Eric PF Chow, Catriona S Bradshaw
BMC INFECTIOUS DISEASES | BMC | Published : 2020
BACKGROUND: Bacterial vaginosis (BV) is estimated to affect 1 in 3 women globally and is associated with obstetric and gynaecological sequelae. Current recommended therapies have good short-term efficacy but 1 in 2 women experience BV recurrence within 6 months of treatment. Evidence of male carriage of BV-organisms suggests that male partners may be reinfecting women with BV-associated bacteria (henceforth referred to as BV-organisms) and impacting on the efficacy of treatment approaches solely directed to women. This trial aims to determine the effect of concurrent male partner treatment for preventing BV recurrence compared to current standard of care. METHODS: StepUp is an open-label, mu..View full abstract
Awarded by Australian NHMRC Project
This trial is funded by an Australian NHMRC Project Grant (APP1138165). The trial Sponsor is Monash University and the trial co-ordinating centre is MSHC. The Sponsor contact is the Monash University Research office (email@example.com).The views expressed are those of the authors and not necessarily those of the NHMRC or Monash University.