Risk factors for candidaemia: A prospective multi-centre case-control study

Abstract

Objectives: Candidaemia carries a mortality of up to 40% and may be related to increasing complexity of medical care. Here, we determined risk factors for the development of candidaemia. Methods: We conducted a prospective, multi-centre, case-control study over 12 months. Cases were aged ≥18 years with at least one blood culture positive for Candida spp. Each case was matched with two controls, by age within 10 years, admission within 6 months, admitting unit, and admission duration at least as long as the time between admission and onset of candidaemia. Results: A total of 118 incident cases and 236 matched controls were compared. By multivariate analysis, risk factors for candidaemia inclu..