Journal article

An infectious diseases perspective on the microbiome and allogeneic stem cell transplant

Olivia C Smibert, Jason A Trubiano, Monica A Slavin, Jason C Kwong

Current Opinion in Infectious Diseases | LIPPINCOTT WILLIAMS & WILKINS | Published : 2020

Abstract

PURPOSE OF REVIEW: The gut microbiome presents a novel source of diagnostic and therapeutic potential to modify post allogeneic stem cell transplant complications. There is an explosion of interest in microbiome research, mostly in the form of single-centre prospective time-series cohorts utilizing a variety of sampling frequencies and metagenomic technologies to sequence the microbiome. The purpose of this review is to summarize important recent publications and contextualize them within what has already been described in this rapidly growing field. RECENT FINDING: Results from observational human cohort and animal transplant models add to the growing body of evidence that the microbiome mo..

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