Journal article

A pan-Canadian prospective study of young women with breast cancer: the rationale and protocol design for the RUBY study

ML Quan, IA Olivotto, NN Baxter, CM Friedenreich, K Metcalfe, E Warner, K MacLennan, JE Stephen, MR Akbari, D Howell, S Narod

Current Oncology | MULTIMED INC | Published : 2020


Introduction: The understanding of the biology and epidemiology of, and the optimal therapeutic strategies for, breast cancer (bca) in younger women is limited. We present the rationale, design, and initial recruitment of Reducing the Burden of Breast Cancer in Young Women (ruby), a unique national prospective cohort study designed to examine the diagnosis, treatment, quality of life, and outcomes from the time of diagnosis for young women with bca. Methods: Over a 4-year period at 33 sites across Canada, the ruby study will use a local and virtual recruitment model to enrol 1200 women with bca who are 40 years of age or younger at the time of diagnosis, before initiation of any treatment. A..

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Funding Acknowledgements

This study is jointly funded by the Canadian Institutes of Health Research and the Canadian Breast Cancer Foundation-National (now Canadian Cancer Society-Research) 5-year grant competition for research about young women with bca. Special thanks to Susan Isherwood phd and Agota Ferenc msc for project and data management in the creation of the cohort and manuscript.