Journal article

Self-Controlled Choice Arises from Dynamic Prefrontal Signals That Enable Future Anticipation

Daiki Tanaka, Ryuta Aoki, Shinsuke Suzuki, Masaki Takeda, Kiyoshi Nakahara, Koji Jimura

Journal of Neuroscience | Society for Neuroscience | Published : 2020

Abstract

Self-control allows humans the patience necessary to maximize reward attainment in the future. Yet it remains elusive when and how the preference to self-controlled choice is formed. We measured brain activity while female and male humans performed an intertemporal choice task in which they first received delayed real liquid rewards (forced-choice trial), and then made a choice between the reward options based on the experiences (free-choice trial). We found that, while subjects were awaiting an upcoming reward in the forced-choice trial, the anterior prefrontal cortex (aPFC) tracked a dynamic signal reflecting the pleasure of anticipating the future reward. Importantly, this prefrontal sign..

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University of Melbourne Researchers

Grants

Awarded by Uehara Memorial Foundation


Funding Acknowledgements

This work was supported by Grants-in-Aid for Scientific Research (KAKENHI) 26350986, 26120711, 17K01989, 17H05957, and 19H04914 (to K.J.); 17H00891 (to K.N.); and 20H00521, 18H04953, 18H04953, 18H05140, and 17K07062 (to M.T.); the Uehara Memorial Foundation (K.J. and M.T.); and the Takeda Science Foundation (K.J. and M.T.). We thank Dr. Kenji Miyamoto and Dr. Norifumi Kawakami for their technical supports. We thank Maoko Yamanaka for administrative assistance.