Journal article

Can post-mortem coronary artery calcium scores aid diagnosis in young sudden death?

Elizabeth D Paratz, Ben Costello, Luke Rowsell, Natalie Morgan, Karen Smith, Tina Thompson, Chris Semsarian, Andreas Pflaumer, Paul James, Dion Stub, Andre La Gerche, Dominica Zentner, Sarah Parsons

Forensic Science, Medicine and Pathology | HUMANA PRESS INC | Published : 2020


This study sought to explore the feasibility and utility of post-mortem coronary artery calcium (CAC) scoring in identifying patients with ischemic heart disease as cause of sudden death. 100 deceased patients aged 18-50 years underwent post-mortem examination in the setting of sudden death. At post-mortem, fifty cases were determined to have ischemic heart disease, and fifty had death attributed to trauma or unascertained causes. The CAC score was calculated in a blinded manner from post-mortem CTs performed on all cases. CAC scores were assessable in 97 non-decomposed cases (feasibility 97%). The median CAC score was 88 Agatston units [IQR 0-286] in patients deceased from ischemic heart di..

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Awarded by NHMRC/NHF

Funding Acknowledgements

This project was not directly funded. EDP is supported by a NHMRC/NHF co-funded Postgraduate Scholarship (APP 1168218), RACP JJ Billings Scholarship and PSA Cardiovascular Scholarship. ALG is supported by a NHF Future Leader Fellowship. DS is supported by a NHF Future Leader Fellowship and Viertel Foundation Grant. CS is supported by a NHMRC Australia Practitioner Fellowship. The EndUCD registry is supported by the Ross Dennerstein Foundation.