Journal article
Severe Impairment of TNF Post-transcriptional Regulation Leads to Embryonic Death
E Clayer, D Dalseno, A Kueh, D Lacey, M Tsai, EH Arvell, VC Wimmer, P Bouillet
Iscience | CELL PRESS | Published : 2020
Abstract
Molecular Biology; Immunology; Developmental Biology
Grants
Awarded by Leukemia and Lymphoma Society
Funding Acknowledgements
We thank J. Stanley, T. Kitson. M. Watters, and G. Siciliano for animal care and expertise; J. Corbin, K. Weston, and T. Nikolaou for automated blood analysis; T. Mak (The Campbell Family Institute for Breast Cancer Research) for TNFR1 KOmice; and J. Silke for TNF KO mice. This work was supported by the Australian NHMRC (Program Grant 461221, Research Fellowship 1042629, Project grant 1127885), the Leukemia and Lymphoma Society (Specialised Center of Research grant 7015), the Arthritis Australia Zimmer fellowship, and infrastructure support from the NHMRC (IRISS), and the Victorian State Government (OIS). The generation of TNFdel4, TNFdel5, TNFdel6, TNFdel4del5, and TNFdel4del6 mice used in this study was supported by the Australian Phenomics Network (APN) and the Australian Government through the National Collaborative Research Infrastructure Strategy (NCRIS) program.