Journal article
Association of Cardiometabolic Multimorbidity and Depression With Cardiovascular Events in Early-Onset Adult Type 2 Diabetes: A Multiethnic Study in the U.S.
JE Dibato, O Montvida, F Zaccardi, JA Sargeant, MJ Davies, K Khunti, SK Paul
Diabetes Care | Published : 2021
DOI: 10.2337/dc20-2045
Abstract
OBJECTIVE To evaluate the temporal patterns of cardiometabolic multimorbidity (CM) and depression in White Caucasians (WCs) and African Americans (AAs) with early-onset type 2 diabetes and their impact on long-term atherosclerotic cardiovascular disease (ASCVD). RESEARCH DESIGN AND METHODS From U.S. electronic medical records, 101,104 AA and 505,336 WC subjects with type 2 diabetes diagnosed between 2000 and 2017 were identified (mean follow-up 5.3 years). Among those without ASCVD at diagnosis, risk of ASCVD and three-point major adverse cardiovascular events (MACE-3) (heart failure, myocardial infarction, or stroke) was evaluated between ethnicities by age-groups. RESULTS The proportion of..
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Funding Acknowledgements
Melbourne EpiCentre gratefully acknowledges support from the National Health and Medical Research Council and the Australian Government's National Collaborative Research Infrastructure Strategy initiative through Therapeutic Innovation Australia. The authors acknowledge Dr. Digsu Koye from the University of Melbourne for supporting this research.