Journal article

Electroconvulsive Therapy in Mania: A Review of 80 Years of Clinical Experience.

Alby Elias, Naveen Thomas, Harold A Sackeim

Am J Psychiatry | Published : 2021


Resistance to pharmacological agents is commonly encountered in the treatment of acute episodes of mania. In contemporary practice guidelines, electroconvulsive therapy (ECT), once a widely used standalone intervention for mania, is no longer considered a first-line treatment. Stigma, logistics, and ethical factors constrain ECT administration in this condition and lead to its underutilization. However, the past three decades have produced promising research regarding the use of ECT in mania. Randomized controlled trials, albeit in limited numbers, the adoption of ultrabrief ECT, examination of the safety and efficacy of combining ECT with pharmacological agents, including lithium, and use o..

View full abstract

University of Melbourne Researchers