Prior exercise enhances skeletal muscle microvascular blood flow and mitigates microvascular flow impairments induced by a high-glucose mixed meal in healthy young men
Lewan Parker, Dale J Morrison, Glenn D Wadley, Christopher S Shaw, Andrew C Betik, Katherine Roberts-Thomson, Gunveen Kaur, Michelle A Keske
The Journal of Physiology | WILEY | Published : 2020
KEY POINTS: Exercise, insulin-infusion and low-glucose mixed-nutrient meal ingestion increases muscle microvascular blood flow which in part facilitates glucose delivery and disposal. In contrast, high-glucose ingestion impairs muscle microvascular blood flow which may contribute to impaired postprandial metabolism. We investigated the effects of prior cycling exercise on postprandial muscle microvascular blood flow responses to a high-glucose mixed-nutrient meal ingested 3 and 24 h post-exercise. Prior exercise enhanced muscle microvascular blood flow and mitigated microvascular impairments induced by a high-glucose mixed meal ingested 3 h post-exercise, and to a lesser extent 24 h post-exe..View full abstract
Awarded by National Heart Foundation Early Career Fellowship
This study was funded by Deakin University. Dr Lewan Parker was supported by a NHMRC& National Heart Foundation Early Career Fellowship (APP1157930).