Journal article

Obesity and Brain Function: The Brain-Body Crosstalk

Sophia X Sui, Julie A Pasco

MEDICINA-LITHUANIA | MDPI | Published : 2020


Dementia comprises a wide range of progressive and acquired neurocognitive disorders. Obesity, defined as excessive body fat tissue, is a common health issue world-wide and a risk factor for dementia. The adverse effects of obesity on the brain and the central nervous system have been the subject of considerable research. The aim of this review is to explore the available evidence in the field of body-brain crosstalk focusing on obesity and brain function, to identify the major research measurements and methodologies used in the field, to discuss the potential risk factors and biological mechanisms, and to identify the research gap as a precursor to systematic reviews and empirical studies i..

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University of Melbourne Researchers


Funding Acknowledgements

S.X.S. was supported by a Deakin Postgraduate Scholarship in conjunction with the Geelong Medical and Hospital Benefits Association (GMHBA); J.A.P. has received speaker fees from Amgen, Eli Lilly and Sanofi-Aventis and funding fromthe National Health and Medical Research Council (NHMRC), Barwon Health, DeakinUniversity, Amgen, the BUPA Foundation, Osteoporosis Australia, Australia and New Zealand Bone and Mineral Society, the Geelong Community Foundation, the Western Alliance, and the Norman Beischer Foundation.