Journal article

Pseudotumor presentation of CMV disease: Diagnostic dilemma and association with immunomodulating therapy

Olivia C Smibert, Cody C Allison, Marcel Doerflinger, Marc Pellegrini, Danny Rischin, Alesha Thai, Monica A Slavin, Camille N Kotton

Transplant Infectious Disease | WILEY | Published : 2020

Abstract

Cytomegalovirus (CMV) is a significant cause of morbidity and mortality in the immunocompromised host. Atypical presentations which include pseudotumors or "cancer mimics" have been described. The etiology of these lesions remains unclear. The authors describe two previously unpublished cases that have arisen in the context of newer immunomodulating therapy and review the existing non-HIV-associated CMV pseudotumors described in the literature.