Journal article
ANALYSIS OF FLUID VOLUME AND ITS IMPACT ON VISUAL ACUITY IN THE FLUID STUDY AS QUANTIFIED WITH DEEP LEARNING
Gregor S Reiter, Christoph Grechenig, Wolf-Dieter Vogl, Robyn H Guymer, Jennifer J Arnold, Hrvoje Bogunovic, Ursula Schmidt-Erfurth
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES | LIPPINCOTT WILLIAMS & WILKINS | Published : 2021
Abstract
PURPOSE: To investigate quantitative differences in fluid volumes between subretinal fluid (SRF)-tolerant and SRF-intolerant treat-and-extend regimens for neovascular age-related macular degeneration and analyze the association with best-corrected visual acuity. METHODS: Macular fluid (SRF and intraretinal fluid) was quantified on optical coherence tomography volumetric scans using a trained and validated deep learning algorithm. Fluid volumes and complete resolution was automatically assessed throughout the study. The impact of fluid location and volumes on best-corrected visual acuity was computed using mixed-effects regression models. RESULTS: Baseline fluid quantifications for 348 eyes f..
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