Treatment interventions to maintain abstinence from alcohol in primary care: systematic review and network meta-analysis
Hung-Yuan Cheng, Luke A McGuinness, Roy G Elbers, Georgina J MacArthur, Abigail Taylor, Alexandra McAleenan, Sarah Dawson, Jose A Lopez-Lopez, Julian PT Higgins, Sean Cowlishaw, Anne Lingford-Hughes, Matthew Hickman, David Kessler
BMJ: British Medical Journal | BMJ PUBLISHING GROUP | Published : 2020
OBJECTIVE: To determine the most effective interventions in recently detoxified, alcohol dependent patients for implementation in primary care. DESIGN: Systematic review and network meta-analysis. DATA SOURCES: Medline, Embase, PsycINFO, Cochrane CENTRAL, ClinicalTrials.gov, and the World Health Organization's International Clinical Trials Registry Platform. STUDY SELECTION: Randomised controlled trials comparing two or more interventions that could be used in primary care. The population was patients with alcohol dependency diagnosed by standardised clinical tools and who became detoxified within four weeks. DATA EXTRACTION: Outcomes of interest were continuous abstinence from alcohol (effe..View full abstract
Awarded by School for Primary Care Research, National Institute for Health Research (NIHR SPCR)
Awarded by NIHR
This review was funded primarily by the School for Primary Care Research, National Institute for Health Research (NIHR SPCR; ref 286). JPTH and MH are NIHR senior investigators. JPTH, MH, and DK are supported by NIHR Bristol Biomedical Research Centre at University Hospitals Bristol and Weston NHS Foundation Trust and the University of Bristol. JPTH is supported by the NIHR Applied Research Collaboration West (ARC West) at University Hospitals Bristol and Weston NHS Foundation Trust. JPTH and MH are supported by the NIHR Health Research Health Protection Research Unit (HPRU) HPRU in Evaluation of Interventions at University of Bristol. LAM is supported by a NIHR doctoral research fellowship (DRF-2018-11-ST2-048). GJM was supported by an NIHR postdoctoral fellowship award (PDF-2013-06-026). This report is independent research supported by the NIHR (postdoctoral fellowship, PDF-2013-06-026). The views expressed in this article are those of the authors and do not necessarily represent those of the UK National Health Service or NIHR. The conduct of the review, writing of the paper, and decision to submit for publication were independent of all research funders. The funders had no role in considering the study design or in the collection, analysis, and interpretation of data, writing of the report, or decision to submit the article for publication.