Journal article
Pilot study of a combined genomic and epidemiologic surveillance program for hospital-acquired multidrug-resistant pathogens across multiple hospital networks in Australia
NL Sherry, CL Gorrie, JC Kwong, RL Stuart, TM Korman, C Marshall, C Higgs, HT Chan, M Graham, PDR Johnson, MJ Leroi, C Reed, MJ Richards, MA Slavin, LJ Worth, BP Howden, ML Grayson
Infection Control and Hospital Epidemiology | CAMBRIDGE UNIV PRESS | Published : 2021
Abstract
Abstract Objectives: To conduct a pilot study implementing combined genomic and epidemiologic surveillance for hospital-acquired multidrug-resistant organisms (MDROs) to predict transmission between patients and to estimate the local burden of MDRO transmission. Design: Pilot prospective multicenter surveillance study. Setting: The study was conducted in 8 university hospitals (2,800 beds total) in Melbourne, Australia (population 4.8 million), including 4 acute-care, 1 specialist cancer care, and 3 subacute-care hospitals. Methods: All clinical and screening isolates from hospital inpatients (April 24 to June 18, 2017) were collected for 6 MDROs: vanA VRE, MRSA, ESBL Escherichia coli (ESBL-..
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Awarded by Department of Health and Human Services, State Government of Victoria
Funding Acknowledgements
This work was supported by the Melbourne Genomics Health Alliance, funded by the State Government of Victoria, Department of Health and Human Services, and the 10 member organizations, and by individual grants from National Health and Medical Research Council of Australia (grant no. GNT1093468 to N.L.S.; grant no. GNT1008549 to J.C.K.; grant no. GNT1105905 to B.P.H.; and grant no. GNT1116576 to M.A.S.).