Journal article

Regional ventilation characteristics during non-invasive respiratory support in preterm infants

Jessica Thomson, Christoph M Ruegger, Elizabeth J Perkins, Prue M Pereira-Fantini, Olivia Farrell, Louise S Owen, David G Tingay

ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION | BMJ PUBLISHING GROUP | Published : 2021

Abstract

OBJECTIVES: To determine the regional ventilation characteristics during non-invasive ventilation (NIV) in stable preterm infants. The secondary aim was to explore the relationship between indicators of ventilation homogeneity and other clinical measures of respiratory status. DESIGN: Prospective observational study. SETTING: Two tertiary neonatal intensive care units. PATIENTS: Forty stable preterm infants born <30 weeks of gestation receiving either continuous positive airway pressure (n=32) or high-flow nasal cannulae (n=8) at least 24 hours after extubation at time of study. INTERVENTIONS: Continuous electrical impedance tomography imaging of regional ventilation during 60 min of quiet b..

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Grants

Awarded by National Health and Medical Research Council Clinical Career Development Fellowship


Awarded by Swiss National Science Foundation Early Postdoctoral Mobility fellowship


Funding Acknowledgements

This study is supported by the Victorian Government Operational Infrastructure Support Program (Melbourne, Australia). DGT is supported by a National Health and Medical Research Council Clinical Career Development Fellowship (grant ID 1053889). CMR is supported by a Swiss National Science Foundation Early Postdoctoral Mobility fellowship (P2ZHP3_161749) and the Milupa Fellowship Award of the Swiss Society of Neonatology. SenTec AG (Landquart, Switzerland) manufactured custom--built electrical impedance tomography (EIT) belts for infants. All EIT hardware was purchased by Murdoch Children's Research Institute without any restrictions.