Journal article

Regional ventilation characteristics during non-invasive respiratory support in preterm infants

J Thomson, CM Rüegger, EJ Perkins, PM Pereira-Fantini, O Farrell, LS Owen, DG Tingay

Archives of Disease in Childhood Fetal and Neonatal Edition | BMJ PUBLISHING GROUP | Published : 2021

Abstract

Objectives To determine the regional ventilation characteristics during non-invasive ventilation (NIV) in stable preterm infants. The secondary aim was to explore the relationship between indicators of ventilation homogeneity and other clinical measures of respiratory status. Design Prospective observational study. Setting Two tertiary neonatal intensive care units. Patients Forty stable preterm infants born <30 weeks of gestation receiving either continuous positive airway pressure (n=32) or high-flow nasal cannulae (n=8) at least 24 hours after extubation at time of study. Interventions Continuous electrical impedance tomography imaging of regional ventilation during 60 min of quiet breath..

View full abstract

University of Melbourne Researchers

Grants

Awarded by State Government of Victoria


Funding Acknowledgements

This study is supported by the Victorian Government Operational Infrastructure Support Program (Melbourne, Australia). DGT is supported by a National Health and Medical Research Council Clinical Career Development Fellowship (grant ID 1053889). CMR is supported by a Swiss National Science Foundation Early Postdoctoral Mobility fellowship (P2ZHP3_161749) and the Milupa Fellowship Award of the Swiss Society of Neonatology. SenTec AG (Landquart, Switzerland) manufactured custom--built electrical impedance tomography (EIT) belts for infants. All EIT hardware was purchased by Murdoch Children's Research Institute without any restrictions.