Journal article

Remineralising effects of fluoride varnishes containing calcium phosphate on artificial root caries lesions with adjunctive application of proanthocyanidin

Jing Cai, Michael F Burrow, David J Manton, Rita Hardiman, Joseph EA Palamara

Dental Materials | ELSEVIER SCI LTD | Published : 2021

Abstract

OBJECTIVES: To evaluate the remineralising effects of fluoride (F) varnishes containing bioavailable calcium-phosphate compound (Ca-P) based remineralisation systems and 5000 ppm F toothpaste (FTP) on root caries lesions (RCLs) and the potential effects of proanthocyanidin (PA) for the treatments of RCLs when used as an adjunct to F regimens. METHODS: Demineralised root dentine and a pH-cycling model were used to mimic RCLs and the oral environment. Remineralising effects of MI VarnishTM (MIV) containing casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and Clinpro™ White Varnish (CPWV) containing tri-calcium phosphate (TCP) along with FTP and PA were evaluated regarding the birefr..

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Grants

Awarded by ADRF


Funding Acknowledgements

This work was supported by Australian Dental Research Foundation (ADRF) Nathan Cochrane Memorial Grant and ADRF grant No. 326-2018. Jing Cai was supported by the China Scholarship Council -University of Melbourne Research Scholarship. The authors appreciate the Bio21 Advanced Microscopy Facility and Ms Su Toulson for the assistance with SEM-EDS analysis.