Remineralising effects of fluoride varnishes containing calcium phosphate on artificial root caries lesions with adjunctive application of proanthocyanidin
Jing Cai, Michael F Burrow, David J Manton, Rita Hardiman, Joseph EA Palamara
Dental Materials | ELSEVIER SCI LTD | Published : 2021
OBJECTIVES: To evaluate the remineralising effects of fluoride (F) varnishes containing bioavailable calcium-phosphate compound (Ca-P) based remineralisation systems and 5000 ppm F toothpaste (FTP) on root caries lesions (RCLs) and the potential effects of proanthocyanidin (PA) for the treatments of RCLs when used as an adjunct to F regimens. METHODS: Demineralised root dentine and a pH-cycling model were used to mimic RCLs and the oral environment. Remineralising effects of MI VarnishTM (MIV) containing casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and Clinpro™ White Varnish (CPWV) containing tri-calcium phosphate (TCP) along with FTP and PA were evaluated regarding the birefr..View full abstract
Awarded by ADRF
This work was supported by Australian Dental Research Foundation (ADRF) Nathan Cochrane Memorial Grant and ADRF grant No. 326-2018. Jing Cai was supported by the China Scholarship Council -University of Melbourne Research Scholarship. The authors appreciate the Bio21 Advanced Microscopy Facility and Ms Su Toulson for the assistance with SEM-EDS analysis.