Journal article
Mode of birth and risk of infection-related hospitalisation in childhood: A population cohort study of 7.17 million births from 4 high-income countries
JE Miller, R Goldacre, HC Moore, J Zeltzer, M Knight, C Morris, S Nowell, R Wood, KW Carter, P Fathima, N de Klerk, T Strunk, J Li, N Nassar, LH Pedersen, DP Burgner
Plos Medicine | PUBLIC LIBRARY SCIENCE | Published : 2020
Abstract
Background The proportion of births via cesarean section (CS) varies worldwide and in many countries exceeds WHO-recommended rates. Long-term health outcomes for children born by CS are poorly understood, but limited data suggest that CS is associated with increased infection-related hospitalisation. We investigated the relationship between mode of birth and childhood infection-related hospitalisation in high-income countries with varying CS rates. Methods and findings We conducted a multicountry population-based cohort study of all recorded singleton live births from January 1, 1996 to December 31, 2015 using record-linked birth and hospitalisation data from Denmark, Scotland, England, and ..
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Awarded by Financial Markets Foundation for Children
Funding Acknowledgements
NdK, KWC, and DPB received funding from National Health and Medical Research Council project grants www.nhmrc.gov.au (GTN1065494: NdK, KWC, DPB), (GTN1045668: HCM, NdK), Fellowship (1034254: HCM), and Senior Research Fellowship (GTN1064629: DPB); JEM received funding from the DHB Foundation; LHP received funding from Health Research Fund of Central Denmark Region; JL received funding from the Novo Nordisk Foundation www.novonordisk.com (NNF18OC0052029), and the Danish Council for Independent Research https://dff.dk/en (DFF-6110-00019); NN received funding from Financial Markets Foundation for Children www.foundationforchildren.com.au; TS received funding from Raine Foundation Clinician Research Fellowship http://rainefoundation.org.au; RG and MK received funding from Public Health England www.gov.uk/government/organisations/publichealth-england, the Li Ka Shing Foundation www.lksf.org, the Robertson Foundation www.robertsonfoundation.org, the Medical Research Council https://mrc.ukri.org, British Heart Foundation www.bhf.org.uk, and the NIHR Oxford Biomedical Research Centre https://oxfordbrc.nihr.ac.uk.The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.