Nanoparticles in pregnancy: the next frontier in reproductive therapeutics

Natasha Pritchard; Tu'uhevaha Kaitu'u-Lino; Lynda Harris; Stephen Tong; Natalie Hannan

Journal article

Nanoparticles in pregnancy: the next frontier in reproductive therapeutics

Natasha Pritchard, Tu'uhevaha Kaitu'u-Lino, Lynda Harris, Stephen Tong, Natalie Hannan

HUMAN REPRODUCTION UPDATE | OXFORD UNIV PRESS | Published : 2021

DOI: 10.1093/humupd/dmaa049

Abstract

BACKGROUND: Nanotechnology involves the engineering of structures on a molecular level. Nanomedicine and nano-delivery systems have been designed to deliver therapeutic agents to a target site or organ in a controlled manner, maximizing efficacy while minimizing off-target effects of the therapeutic agent administered. In both reproductive medicine and obstetrics, developing innovative therapeutics is often tempered by fears of damage to the gamete, embryo or developing foetus or of negatively impacting a woman's reproductive potential. Thus, nanomedicine delivery systems may provide alternative targeted intervention strategies, treating the source of the disease and minimizing long-term con..

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University of Melbourne Researchers

Tu'uhevaha Kaitu'u-Lino Author Obstetrics and Gynaecology Royal Women's Hospital/Mercy

Stephen Tong Author Obstetrics and Gynaecology Royal Women's Hospital/Mercy

Natasha Pritchard Author Obstetrics and Gynaecology Royal Women's Hospital/Mercy

Natalie Hannan Author Obstetrics and Gynaecology Royal Women's Hospital/Mercy

Related Projects (4)

IDENTIFICATION OF WHICH FETAL GROWTH CHARTS AND BIRTHWEIGHT CENTILES ARE BEST ABLE TO IDENTIFY INFANTS AND MOTHERS AT RISK OF ADVERSE OBSTETRIC AND PERINATAL OUTCOMES

Preeclampsia, one of the most serious complications of pregnancy, affects around 3-8% of all pregnancies. Sadly, there is no treatment. We h..

TRANSLATING NEW THERAPEUTICS AND DIAGNOSTICS FOR MAJOR PREGNANCY COMPLICATIONS

My research is focussed on tackling major complications of pregnancy that are a threat to the lives of both mother’s and babies. We are deve..

DEVELOPMENT OF NOVEL THERAPEUTICS TO PREVENT OR TREAT PREECLAMPSIA

Preeclampsia, a major pregnancy complication, affects ~3-8% of pregnancies. There is no cure. We have developed new strategies to tackle the..

NEW DIAGNOSTICS TO PREDICT PREECLAMPSIA AND FETAL GROWTH RESTRICTION

Grants

Awarded by NHMRC Postgraduate Research Scholarship

Awarded by NHMRC

Funding Acknowledgements

NHMRC Postgraduate Research Scholarship (#1150828 to N.P.); NHMRC (#1159261 to T.K.-L., #1136418 to S.T. and #1146128 to N.H. for providing salary support).