Journal article

Prediction Models for Physical, Cognitive, and Mental Health Impairments After Critical Illness: A Systematic Review and Critical Appraisal

Kimberley J Haines, Elizabeth Hibbert, Joanne McPeake, Brian J Anderson, Oscar Joseph Bienvenu, Adair Andrews, Nathan E Brummel, Lauren E Ferrante, Ramona O Hopkins, Catherine L Hough, James Jackson, Mark E Mikkelsen, Nina Leggett, Ashley Montgomery-Yates, Dale M Needham, Carla M Sevin, Becky Skidmore, Mary Still, Maarten van Smeden, Gary S Collins Show all

Critical Care Medicine | LIPPINCOTT WILLIAMS & WILKINS | Published : 2020


OBJECTIVES: Improved ability to predict impairments after critical illness could guide clinical decision-making, inform trial enrollment, and facilitate comprehensive patient recovery. A systematic review of the literature was conducted to investigate whether physical, cognitive, and mental health impairments could be predicted in adult survivors of critical illness. DATA SOURCES: A systematic search of PubMed and the Cochrane Library (Prospective Register of Systematic Reviews ID: CRD42018117255) was undertaken on December 8, 2018, and the final searches updated on January 20, 2019. STUDY SELECTION: Four independent reviewers assessed titles and abstracts against study eligibility criteria...

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Awarded by NIH

Awarded by National Institute on Aging

Awarded by Cancer Research UK

Awarded by NIH/NHLBI grants

Funding Acknowledgements

Supported, in part, by Society of Critical Care Medicine (SCCM). The information specialist was funded by SCCM to conduct the search for this review.Drs. Haines', McPeake's, Ferrante's, and Sevin's institutions received funding from the Society of Critical Care Medicine (SCCM). Drs. Haines from a Thrive grant from SCCM, and Drs. McPeake and Sevin received funding from SCCM. Dr. McPeake's institution received funding from THIS Institute (University of Cambridge). Drs. Anderson's and Ferrante's institutions received funding from National Institutes of Health (NIH)/National Heart, Lung, and Blood Institute (NHLBI). Dr. Anderson's institution received funding from the American Thoracic Society Foundation. Drs. Anderson, Brummel, Ferrante, Jackson, Needham, and Harhay received support for article research from the NIH. Dr. Brummel's institution received funding from the NIH, and he received funding from Merck. Drs. Hough and Skidmore disclosed work for hire. Dr. Ferrante is supported by a Beeson award from the National Institute on Aging (K76 057023). Dr. Needham's institution received funding from NIH (R01HL132887) evaluating nutrition and exercise in acute respiratory failure. For purposes of this multisite trial, Baxter Healthcare Corporation has provided an unrestricted research grant and donated amino acid product. Also, two study sites (not his University/site) have received an equipment loan from Reck Medical Devices. Dr. Collins was supported by the National Institute for Health Research Biomedical Research Centre, Oxford, and Cancer Research UK (program grant: C49297/A27294). Dr. Harhay's institution received funding from NIH/NHLBI grants K99HL141678 and R00HL141678. BJA was supported by K23HL140482 from the U.S. National Institutes of Health. The remaining authors have disclosed that they do not have any potential conflicts of interest.