Journal article

Nicotine replacement treatment, e-cigarettes and an online behavioural intervention to reduce relapse in recent ex-smokers: a multinational four-arm RCT

Hayden J McRobbie, Anna Phillips-Waller, Catherine El Zerbi, Ann McNeill, Peter Hajek, Francesca Pesola, James Balmford, Stuart G Ferguson, Lin Li, Sarah Lewis, Ryan J Courtney, Coral Gartner, Linda Bauld, Ron Borland

Health Technology Assessment | NIHR JOURNALS LIBRARY | Published : 2020


BACKGROUND: Relapse remains an unresolved issue in smoking cessation. Extended stop smoking medication use can help, but uptake is low and several behavioural relapse prevention interventions have been found to be ineffective. However, opportunistic 'emergency' use of fast-acting nicotine replacement treatment or electronic cigarettes may be more attractive and effective, and an online behavioural Structured Planning and Prompting Protocol has shown promise. The present trial aimed to evaluate the clinical effectiveness and cost-effectiveness of these two interventions. DESIGN: A randomised controlled trial. SETTING: English stop smoking services and Australian quitlines, Australian social m..

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Awarded by National Health and Medical Research Council, Canberra, ACT, Australia

Funding Acknowledgements

This project was funded by the National Institute for Health Research (NIHR) Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 24, No. 68. See the NIHR Journals Library website for further project information. Funding was also provided by the National Health and Medical Research Council, Canberra, ACT, Australia (NHMRC APP1095880). Public Health England provided the funds to purchase the nicotine products in England.