Journal article

Baseline liver function tests and full blood count indices and their association with progression of chronic kidney disease and renal outcomes in Aboriginal and Torres Strait Islander people: the eGFR follow- up study

Sandawana William Majoni, Federica Barzi, Wendy Hoy, Richard J MacIsaac, Alan Cass, Louise Maple-Brown, Jaquelyne T Hughes

BMC Nephrology | BMC | Published : 2020

Abstract

BACKGROUND: Determination of risks for chronic kidney disease (CKD) progression could improve strategies to reduce progression to ESKD. The eGFR Study recruited a cohort of adult Aboriginal and Torres Strait Islander people (Indigenous Australians) from Northern Queensland, Northern Territory and Western Australia, aiming to address the heavy CKD burden experienced within these communities. METHODS: Using data from the eGFR study, we explored the association of baseline liver function tests (LFTs) (alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma-glutamyl transpeptidase (GGT), bilirubin and albumin) and full blood count (FBC) indices (white blood cell and red blood cell coun..

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Grants

Awarded by National Health and Medical Research Council of Australia (NHMRC)


Awarded by Kidney Health Australia, NHMRC Program


Awarded by NHMRC


Funding Acknowledgements

The eGFR study was funded by the National Health and Medical Research Council of Australia (NHMRC, Project Grants no. 545202 and no. 1021460), with additional support from Kidney Health Australia, NHMRC Program Grant (no. 631947), the Colonial Foundation, Diabetes Australia Research Trust, Rebecca L Cooper Foundation and SeaSwift, Thursday Island. LJM-B was supported by an NHMRC Fellowship (no. 605837) and NHMRC Practitioner Fellowship (no. 1078477); FB was supported by NHMRC Program Grant (no. 631947); JTH was supported by NHMRC Fellowship no. 1174758, 1092576 and Royal Australian College of Physicians (RACP) Jacquot Research Establishment Award;