The case for an HIV cure and how to get there
Mark Dybul, Timothy Attoye, Solange Baptiste, Peter Cherutich, Francois Dabis, Steven G Deeks, Carl Dieffenbach, Brian Doehle, Maureen M Goodenow, Adam Jiang, Dominic Kemps, Sharon R Lewin, Murray M Lumpkin, Lauren Mathae, Joseph M McCune, Thumbi Ndung'u, Moses Nsubuga, Holly L Peay, John Pottage, Mitchell Warren Show all
The Lancet HIV | ELSEVIER INC | Published : 2021
In light of the increasing global burden of new HIV infections, growing financial requirements, and shifting funding landscape, the global health community must accelerate the development and delivery of an HIV cure to complement existing prevention modalities. An effective curative intervention could prevent new infections, overcome the limitations of antiretroviral treatment, combat stigma and discrimination, and provide a sustainable financial solution for pandemic control. We propose steps to plan for an HIV cure now, including defining a target product profile and establishing the HIV Cure Africa Acceleration Partnership (HCAAP), a multidisciplinary public-private partnership that will ..View full abstract
This work was supported by the Bill & Melinda Gates Foundation. The views expressed in this publication are those of the authors and do not necessarily represent the views of the institutions with which the authors are affiliated. The authors would like to acknowledge those who attended and supported the 2019 Sunnylands Summit: the path toward ending HIV (Sani Aliyu, Gregg H Alton, Francoise Barre-Sinoussi, Linda-Gail Bekker, Peter Cherutich, Matt Craven, Francois Dabis, Steve G Deeks, Mark Dybul, Robert Fallon, Mark Feinberg, Diana Finzi, Maureen M Goodenow, Eric Goosby, Daria J Hazuda, George Jagoe, Rowena Johnston, Rosanne Lamplough, Ambassador David J Lane, Ellen LaPointe, Sharon R Lewin, Joseph M McCune, Gary J Nabel, Thumbi Ndung'u, Moses Nsubuga, John Pottage, Ram Prasad, David Ripin, Yiming Shao, Izukanji Sikazwe, Elhadj As Sy, Joseph D Tucker, Jay Varma, Mitchell Warren, Wendy Wertheimer, Jack Whitescarver, and Matthew C Wilson, many of whom contributed to the content and writing of this paper). The authors also acknowledge the support of the International AIDS Society and the Annenberg Trust at Sunnylands in hosting the meeting.