Journal article

Receipt of infant HIV DNA PCR test results is associated with a reduction in retention of HIV-exposed infants in integrated HIV care and healthcare services: a quantitative sub-study nested within a cluster randomised trial in rural Malawi

Elasma Milanzi, Victor Mwapasa, Jessica Joseph, Aurelie Jousset, Timothy Tchereni, Andrews Gunda, Jennipher Phiri, Jeanette C Reece

BMC PUBLIC HEALTH | BMC | Published : 2020

Abstract

BACKGROUND: Retention of HIV-infected mothers in integrated HIV and healthcare facilities is effective at reducing mother-to-child-transmission (MTCT) of HIV. In the context of Option B+, we examined maternal and HIV-exposed infant retention across three study arms to 18 months postpartum: mother-and-infant clinics (MIP), MIP with short-messaging service (MIP + SMS) and standard of care (SOC). In particular, we focused on the impact of mothers receiving an infant's HIV PCR test result on maternal and infant study retention. METHODS: A quantitative sub-study nested within a cluster randomised trial undertaken between May 2013 and August 2016 across 30 healthcare facilities in rural Malawi enr..

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Grants

Awarded by National Health Medical Research Council (NHMRC)


Funding Acknowledgements

The PRIME Project was funded by the World Health Organization through an award for the Integrating and Scaling up PMTCT through Implementation Research (INSPIRE) initiative from Global Affairs Canada.E. Milanzi was supported by the Victorian Centre for Biostatistics. J. C. Reece was supported by a National Health Medical Research Council (NHMRC) Research Fellowship (APP1120081). The funding bodies had no role in the study design, data collection, analysis, interpretation of data or writing of this manuscript.