Journal article

Role of Computed Tomography Perfusion in Identification of Acute Lacunar Stroke Syndromes

Carlos Garcia-Esperon, Milanka Visser, Leonid Churilov, Ferdinand Miteff, Andrew Bivard, Thomas Lillicrap, Christopher R Levi, Neil J Spratt, Mark W Parsons

Stroke | LIPPINCOTT WILLIAMS & WILKINS | Published : 2021


BACKGROUND AND PURPOSE: Lacunar syndromes correlate with a lacunar stroke on imaging in 50% to 60% of cases. Computed tomography perfusion (CTP) is becoming the preferred imaging modality for acute stroke triage. We aimed to estimate the sensitivity, specificity, and predictive values for noncontrast computed tomography and CTP in lacunar syndromes, and for cortical, subcortical, and posterior fossa regions. METHODS: A retrospective analysis of confirmed ischemic stroke patients who underwent acute CTP and follow-up magnetic resonance imaging between 2010 and 2018 was performed. Brain noncontrast computed tomography and CTP were assessed independently by 2 stroke neurologists. Receiver opera..

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Funding Acknowledgements

Dr Garcia-Esperon reports that this research was supported by the Australian Government Research Training Program Scholarship. Dr Spratt reports grants from National Health and Medical Research Council and grants from National Heart Foundation during the conduct of the study outside the submitted work. Dr Parsons reports other from Siemens, other from Canon/Toshiba, and other from Apollo Medical Imaging outside the submitted work. The other authors report no conflicts.