Journal article

Influence of context and setting on the mental health and wellbeing outcomes of ayahuasca drinkers: results of a large international survey

Daniel Perkins, Violeta Schubert, Hana Simonova, Luís Fernando Tófoli, José Carlos Bouso, Miroslav Horák, Nicole Leite Galvão-Coelho, Jerome Sarris

Frontiers in Pharmacology | Frontiers Media | Published : 2021


Ayahuasca is a traditional plant decoction containing N,N-dimethyltryptamine (DMT) and various β-carbolines including harmine, harmaline and tetrahydroharmine, which has been used ceremonially by Amazonian Indigenous groups for healing and spiritual purposes. Use of the brew has now spread far beyond its original context of consumption to North America, Europe and Australia in neo-shamanic settings as well as Christian syncretic churches. While these groups have established their own rituals and protocols to guide use, it remains unknown the extent to which the use of traditional or non-traditional practices may affect drinkers’ acute experiences, and longer term wellbeing and mental health ..

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