The investigation of bone fracture healing under intramembranous and endochondral ossification
Smriti Ghimire, Saeed Miramini, Glenn Edwards, Randi Rotne, Jiake Xu, Peter Ebeling, Lihai Zhang
BONE REPORTS | ELSEVIER | Published : 2021
After trauma, fractured bone starts healing directly through bone union or indirectly through callus formation process. Intramembranous and endochondral ossification are two commonly known mechanisms of indirect healing. The present study investigated the bone fracture healing under intramembranous and endochondral ossification by developing theoretical models in conjunction with performing a series of animal experiments. Using experimentally determined mean bone densities in sheep tibia stabilized by the Locking Compression Plate (LCP) fixation system, the research outcomes showed that intramembranous and endochondral ossification can be described by Hill Function with two unique sets of fu..View full abstract
Awarded by AOTRAUMA Asia Pacific
Awarded by AOA Research Foundation
The authors would like to thank Johnson & Johnson Medical, The g (2015-2016), AOTRAUMA Asia Pacific (AOTAP14-02, 2014-2015) and AOA Research Foundation (Project grant 403) for their support.