Use of Local Antibiogram Data and Antimicrobial Importance Ratings to Select Optimal Empirical Therapies for Urinary Tract Infections in Dogs and Cats
Ri Scarborough, Kirsten Bailey, Bradley Galgut, Adam Williamson, Laura Hardefeldt, James Gilkerson, Glenn Browning
Antibiotics | MDPI AG | Published : 2020
International and Australian veterinary antimicrobial use guidelines recommend amoxicillin or trimethoprim-sulfonamide (TMS) for the empirical treatment of sporadic urinary tract infections (UTIs) in dogs and cats. However, in practice, these antibiotics are rarely used, and no large-scale analyses have examined the antibiograms of bacteria isolated from UTIs to validate these recommendations in Australia. We analyzed five years of urine culture and antimicrobial susceptibility data from an Australian veterinary laboratory. The analysis included 6196 urinary isolates from dogs and cats, 78% of which were from samples submitted by first-opinion veterinary clinics. Escherichia coli, Enterococc..View full abstract
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Awarded by National Health and Medical Research Council of Australia through the Centres of Research Excellence Scheme
This research was funded by the National Health and Medical Research Council of Australia through the Centres of Research Excellence Scheme, Grant no. 1079625 (National Centre for Antimicrobial Stewardship). K.B. is also funded by the NHMRC through the Centres of Research Excellence Scheme (National Centre for Antimicrobial Stewardship). L.H. is funded by the Australian Research Council through the Discovery Early Career Research Award program. R.S. was a recipient of an Australian Postgraduate Award scholarship.