Functional electrical stimulation in-bed cycle ergometry in mechanically ventilated patients: a multicentre randomised controlled trial
Sue Berney, Ramona O Hopkins, Joleen Wyn Rose, Rene Koopman, Zudin Puthucheary, Amy Pastva, Ian Gordon, Elizabeth Colantuoni, Selina M Parry, Dale M Needham, Linda Denehy
THORAX | BMJ PUBLISHING GROUP | Published : 2021
PURPOSE: To investigate the effect of functional electrical stimulation-assisted cycle ergometry (FES-cycling) on muscle strength, cognitive impairment and related outcomes. METHODS: Mechanically ventilated patients aged ≥18 years with sepsis or systemic inflammatory response syndrome were randomised to either 60 min of FES-cycling >5 days/week while in the intensive care unit (ICU) plus usual care rehabilitation versus usual care rehabilitation alone, with evaluation of two primary outcomes: (1) muscle strength at hospital discharge and (2) cognitive impairment at 6-month follow-up. RESULTS: We enrolled 162 participants, across four study sites experienced in ICU rehabilitation in Australia..View full abstract
Related Projects (1)
National Health and Medical Research Council of Australia, the Mrs. Sheila S. Pakula and Dr Lawrence C. Pakula Patient Recovery Fund in Pulmonary and Critical Care Medicine at Johns Hopkins University, The American Thoracic Society Foundation Unrestricted Research Grant (AMP); Intensive Care Foundation of Australia and Austin Health Medical Research Fund. Restorative Therapies provided the RT 300 supine cycle ergometer to the Austin Health site.