Journal article
Rehabilitation for ataxia study: protocol for a randomised controlled trial of an outpatient and supported home-based physiotherapy programme for people with hereditary cerebellar ataxia
Sarah C Milne, Louise A Corben, Melissa Roberts, David Szmulewicz, J Burns, Anneke C Grobler, Shannon Williams, Jillian Chua, Christina Liang, Phillipa J Lamont, Alison C Grootendorst, Libby Massey, Carolyn Sue, Kim Dalziel, Desiree LaGrappe, Liz Willis, Aleka Freijah, Paul Gerken, Martin B Delatycki
BMJ Open | BMJ PUBLISHING GROUP | Published : 2020
Abstract
INTRODUCTION: Emerging evidence indicates that rehabilitation can improve ataxia, mobility and independence in everyday activities in individuals with hereditary cerebellar ataxia. However, with the rarity of the genetic ataxias and known recruitment challenges in rehabilitation trials, most studies have been underpowered, non-randomised or non-controlled. This study will be the first, appropriately powered randomised controlled trial to examine the efficacy of an outpatient and home-based rehabilitation programme on improving motor function for individuals with hereditary cerebellar ataxia. METHODS AND ANALYSIS: This randomised, single-blind, parallel group trial will compare a 30-week reha..
View full abstractGrants
Awarded by Australian Government Medical Research Future Fund (MRFF) Lifting Clinical Trials and Registries Capacity Program Grant
Awarded by Rebecca L Cooper grant
Awarded by MRFF Career Development Fellowship
Funding Acknowledgements
This work was supported by an Australian Government Medical Research Future Fund (MRFF) Lifting Clinical Trials and Registries Capacity Program Grant, number (APP1152226) and a Rebecca L Cooper grant, number (PG2018135). LC is funded by a MRFF Career Development Fellowship, number (APP1143098). The funders are not involved in the study design, the collection, analysis and interpretation of data, nor the writing of the manuscript.