Journal article

Fluorescent Nanodiamonds Embedded in Poly-epsilon-Caprolactone Fibers as Biomedical Scaffolds

Vincenzo Guarino, Iriczalli Cruz-Maya, Philipp Reineck, Hiroshi Abe, Takeshi Ohshima, Kate Fox, Andrew D Greentree, Brant C Gibson, Luigi Ambrosio

ACS Applied Nano Materials | AMER CHEMICAL SOC | Published : 2020

Abstract

Fluorescent nanodiamonds (fNDs) are emerging as important tools for imaging and sensing in biology, which enable the optical detection, for example, of temperature and magnetic fields at the nanoscale. At the same time, their unique physicochemical properties allow fNDs to drastically improve the properties of nanocomposites. Here, we report the integration of fNDs into electrospun poly-ϵ-caprolactone (PCL) fibers and the use of the resulting hybrid material as a nontoxic and multifunctional bioscaffold. We investigate the morphology, size distribution, optical properties, wettability, and biocompatibility of PCL fibers containing 0.2 and 0.4 wt % fNDs and demonstrate the quantum sensing cap..

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Grants

Awarded by Australian Research Council (ARC) through its Centre of Excellence for Nanoscale BioPhotonics


Awarded by Australian Research Council (ARC) through LIEF program


Awarded by ARC DECRA Fellowship scheme


Awarded by ARC Future Fellowship scheme


Awarded by INCIPIT COFUND H2020 Marie Sklodowska-Curie project


Funding Acknowledgements

This work was supported by the Australian Research Council (ARC) through its Centre of Excellence for Nanoscale BioPhotonics (grant no. CE140100003) and the LIEF program (grant no. LE160100051). P.R. acknowledges funding through the RMIT Vice-Chancellor's Research Fellowship and ARC DECRA Fellowship scheme (grant no. DE200100279). A.D.G. acknowledges funding through the ARC Future Fellowship scheme (grant no. FT160100357). Part of this study was carried out within the framework of the QST International Research Initiative. I.C.M. thanks INCIPIT COFUND H2020 Marie Sklodowska-Curie project (grant n. 665403) for her doctoral scholarship. SEM was supported by LAMEST Labs of the Italian National Research Council.