Fetal Growth Trajectories and Their Association with Maternal, Cord Blood, and 5-year Child Adipokines
HC Bartels, AA Geraghty, EC O'Brien, A Kranidi, J Mehegan, C Yelverton, CM McDonnell, FM McAuliffe
Journal of Nutrition and Metabolism | HINDAWI LTD | Published : 2020
Background: The growth of the fetus is a complex process influenced by multiple factors. Studies have highlighted the important role of biochemical growth markers such as leptin and adiponectin on fetal growth. Objective: To compare fetal growth trajectories with biochemical growth markers from maternal blood samples at 28 weeks' gestation, cord blood samples at birth, and in child blood samples at 5 years of age from mother-infant pairs who were part of the longitudinal ROLO study. Methods: 781 mother-infant pairs from the ROLO and ROLO Kids study were included. Ultrasound measurements and birth weight were used to develop fetal growth trajectory groups for estimated abdominal circumference..View full abstract
This research was supported by HRB Health Research Centre for Health and Diet Research, the Health Research Board Ireland, the National Maternity Hospital Medical Fund, and the European Union's Seventh Framework Programme (FP7/2007-2013).