Genetic diversity and quantification of human mastadenoviruses in wastewater from Sydney and Melbourne, Australia
Jennifer H Lun, Nicholas D Crosbie, Peter A White
The Science of The Total Environment | ELSEVIER | Published : 2019
Human mastadenoviruses (HAdVs) are DNA viruses that can cause a wide range of clinical diseases, including gastroenteritis, respiratory illnesses, conjunctivitis, and in more severe cases hepatitis, pancreatitis and disseminated diseases. HAdV infections are generally asymptomatic or self-limiting, but can cause adverse outcomes within vulnerable populations. Since most HAdV serotypes replicate within the human gastrointestinal tract, high levels of HAdV DNA are excreted into wastewater systems. In this study, we identified the genetic diversity of HAdV at a population level using wastewater samples collected from Sydney and Melbourne from 2016 to 2017, with the use of next generation sequen..View full abstract
Related Projects (2)
Awarded by National Health and Medical Research Council
This Australian research was supported by funding from Melbourne Water Corporation and the National Health and Medical Research Council (project no. APP1083139 and APP1123135). Jennifer Lun was supported by an Australian Postgraduate Award and a Water Research Australia Scholarship.