Reduced Impact of Endovascular Thrombectomy on Disability in Real-World Practice, Relative to Randomized Controlled Trial Evidence in Australia
Lan Gao, Elise Tan, Marj Moodie, Mark Parsons, Neil J Spratt, Christopher Levi, Kenneth Butcher, Timothy Kleinig, Bernard Yan, Chushuang Chen, Longting Lin, Philip Choi, Andrew Bivard
Frontiers in Neurology | FRONTIERS MEDIA SA | Published : 2020
Background and Aims: Disability-adjusted life years (DALYs) are an important measure of the global burden of disease that informs patient outcomes and policy decision-making. Our study aimed to compare the DALYs saved by endovascular thrombectomy (EVT) in the Australasian-based EXTEND-IA trial vs. clinical registry data from EVT in Australian routine clinical practice.Methods: The 3-month modified Rankin scale (mRS) outcome and treatment status of consecutively enrolled Australian patients with large vessel occlusion (LVO) stroke were taken from the International Stroke Perfusion Imaging Registry (INSPIRE). DALYs were calculated as the summation of years of life lost (YLL) due to premature d..View full abstract
Awarded by Australian NHMRC/NHF
NS was supported by a cofunded Australian NHMRC/NHF Career Development/Future Leader Fellowship GNT1110629/100827.