Extubation Failure and Major Adverse Events Secondary to Extubation Failure Following Neonatal Cardiac Surgery∗

Abstract

Objectives: To describe the prevalence and consequences of major adverse events secondary to extubation failure after neonatal cardiac surgery. Design: A single-center cohort study. Setting: A medical-surgical, 30-bed PICU in Victoria, Australia. Patients: One thousand one hundred eighty-eight neonates less than or equal to 28 days old who underwent cardiac surgery from January 2007 to December 2018. Interventions: None. Measurements and Main Results: Extubation failure was defined as unplanned reintubation within 72 hours after a planned extubation. Major adverse event was defined as one or more of cardiac arrest, emergency chest reopening, extracorporeal membrane oxygenation, or death with..