The impact of posttraumatic stress disorder on event-related potentials in affective and non-affective paradigms: A systematic review with meta-analysis

LN Miller; JG Simmons; S Whittle; D Forbes; K Felmingham

Journal article

The impact of posttraumatic stress disorder on event-related potentials in affective and non-affective paradigms: A systematic review with meta-analysis

LN Miller, JG Simmons, S Whittle, D Forbes, K Felmingham

Neuroscience and Biobehavioral Reviews | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2021

DOI: 10.1016/j.neubiorev.2020.12.027

Abstract

Post-traumatic stress disorder (PTSD) is associated with neural processing deficits affecting early automatic and later conscious processing. Event-related Potentials (ERPs) are high resolution indices of automatic and conscious processing, but there are no meta-analyses that have examined automatic and conscious ERPs in PTSD across multiple paradigms. This systematic review examined 69 studies across affective and non-affective auditory and visual paradigms. Individuals with PTSD were compared to trauma-exposed and non-trauma controls on ERPs reflecting automatic (N1, P1, N2, P2) and conscious (P3, LPP) processing. Trauma exposure was associated with increased automatic ERP amplitudes to ir..

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University of Melbourne Researchers

Julian Simmons Author

Sarah Whittle Author

David Forbes Author

Kim Felmingham Author

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Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

[ "LNM was supported by a National Health and Medical Research Council Program Grant (1073041) Australia.", "SW was supported by a National Health and Medical Research Council Career Development Fellowship (1125504) Australia." ]