Journal article

The Relationship between Negative Symptoms and Both Emotion Management and Non-social Cognition in Schizophrenia Spectrum Disorders

Caitlin OB Yolland, Sean P Carruthers, Wei Lin Toh, Erica Neill, Philip J Sumner, Elizabeth HX Thomas, Eric J Tan, Caroline Gurvich, Andrea Phillipou, Tamsyn E Van Rheenen, Susan L Rossell



OBJECTIVE: There is ongoing debate regarding the relationship between clinical symptoms and cognition in schizophrenia spectrum disorders (SSD). The present study aimed to explore the potential relationships between symptoms, with an emphasis on negative symptoms, and social and non-social cognition. METHOD: Hierarchical cluster analysis with k-means optimisation was conducted to characterise clinical subgroups using the Scale for the Assessment of Negative Symptoms and Scale for the Assessment of Positive Symptoms in n = 130 SSD participants. Emergent clusters were compared on the MATRICS Consensus Cognitive Battery, which measures non-social cognition and emotion management as well as demo..

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Awarded by Australian National Health and Medical Research Council

Awarded by NHMRC

Funding Acknowledgements

Participants for this study were sourced, in part, through the Cognitive and Genetic Explanations of Mental Illness (CAGEMIS) bio-databank, which is supported by the Australian National Health and Medical Research Council Project Grant (GNT1060664 awarded to SLR). SLR holds an NHMRC Senior Research Fellowship (GNT1154651); EJT (GNT1142424), CG (GNT0546262) and TEVR (1088785) hold NHMRC Early Career Research Fellowships. None of the funding sources played any role in the study design; collection, analysis or interpretation of data; in the writing of the report; or in the decision to submit the paper for publication.