Journal article

Modeling Stroke Patient Transport for All Patients With Suspected Large-Vessel Occlusion

Jessalyn K Holodinsky, Tyler S Williamson, Andrew M Demchuk, Henry Zhao, Luke Zhu, Michael J Francis, Mayank Goyal, Michael D Hill, Noreen Kamal

JAMA Neurology | AMER MEDICAL ASSOC | Published : 2018

Abstract

Importance: Ischemic stroke with large-vessel occlusion can be treated with alteplase and/or endovascular therapy; however, the administration of each treatment is time sensitive. Objective: To identify the optimal triage and transport strategy: direct to the endovascular center (mothership) or immediate alteplase treatment followed by transfer to the endovascular center (drip and ship), for all patients with suspected large-vessel occlusion stroke. Design Setting, and Participants: This was a theoretical, conditional probability modeling study. Existing data from clinical trials of stroke treatment were used for model generation. The study was conducted from February 1, 2017, to March 1, 20..

View full abstract