Journal article

Modeling Stroke Patient Transport for All Patients With Suspected Large-Vessel Occlusion

Jessalyn K Holodinsky, Tyler S Williamson, Andrew M Demchuk, Henry Zhao, Luke Zhu, Michael J Francis, Mayank Goyal, Michael D Hill, Noreen Kamal

JAMA Neurology | AMER MEDICAL ASSOC | Published : 2018


Importance: Ischemic stroke with large-vessel occlusion can be treated with alteplase and/or endovascular therapy; however, the administration of each treatment is time sensitive. Objective: To identify the optimal triage and transport strategy: direct to the endovascular center (mothership) or immediate alteplase treatment followed by transfer to the endovascular center (drip and ship), for all patients with suspected large-vessel occlusion stroke. Design Setting, and Participants: This was a theoretical, conditional probability modeling study. Existing data from clinical trials of stroke treatment were used for model generation. The study was conducted from February 1, 2017, to March 1, 20..

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