Journal article

The association between migrant status and transition in an ultra-high risk for psychosis population

B O’Donoghue, H Geros, H Sizer, J Addington, GP Amminger, CE Beaden, KS Cadenhead, TD Cannon, BA Cornblatt, GE Berger, EYH Chen, L de Haan, JA Hartmann, IB Hickie, HK Ising, S Lavoie, A Lin, C Markulev, DH Mathalon, TH McGlashan Show all

Social Psychiatry and Psychiatric Epidemiology | SPRINGER HEIDELBERG | Published : 2021

Abstract

Purpose: Migrant status is one of the most replicated and robust risk factors for developing a psychotic disorder. This study aimed to determine whether migrant status in people identified as Ultra-High Risk for Psychosis (UHR) was associated with risk of transitioning to a full-threshold psychotic disorder. Methods: Hazard ratios for the risk of transition were calculated from five large UHR cohorts (n = 2166) and were used to conduct a meta-analysis using the generic inverse-variance method using a random-effects model. Results: 2166 UHR young people, with a mean age of 19.1 years (SD ± 4.5) were included, of whom 221 (10.7%) were first-generation migrants. A total of 357 young people tran..

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