Journal article

The Effect of Acute Physical Exercise on NK-Cell Cytolytic Activity: A Systematic Review and Meta-Analysis

Christopher Rumpf, Sebastian Proschinger, Alexander Schenk, Wilhelm Bloch, Amit Lampit, Florian Javelle, Philipp Zimmer

Sports Medicine | ADIS INT LTD | Published : 2021

Abstract

BACKGROUND: Data on changes in natural killer cell cytolytic activity (NKCA) in response to acute physical exercise are contradictory. OBJECTIVE: The aim of this systematic review, meta-analysis and meta-regression is to (1) examine the effect of acute physical exercise on NKCA, (2) shed more light on the moderating factors, and (3) test the assumption of NKCA suppression subsequent to performing sports. METHODS: Two comparisons of NKCA were performed: (1) pre- versus post-exercise and (2) pre-exercise versus recovery. Data were acquired through a systematic search of MEDLINE (via PubMed), Scopus, and SportDiscus. Studies were eligible for inclusion if the effect of acute physical exercise w..

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Funding Acknowledgements

This research was conducted in the absence of any external funding. Open Access funding enabled and organized by Projekt DEAL.