Journal article
Nonquinolone options for the treatment of Mycoplasma genitalium in the era of increased resistance
M Doyle, LA Vodstrcil, EL Plummer, I Aguirre, CK Fairley, CS Bradshaw
Open Forum Infectious Diseases | OXFORD UNIV PRESS INC | Published : 2020
DOI: 10.1093/ofid/ofaa291
Abstract
In the era of increasing macrolide- and quinolone-resistant Mycoplasma genitalium (MG), we report the efficacy of 2 nonquinolone antimicrobials in patients with limited treatment options. Pristinamycin + doxycycline cured 75% (95% CI, 64%-85%), and minocycline cured 71% (95% CI, 54%-85%) of cases. These data provide useful estimates to inform clinical practice.
Grants
Awarded by National Health and Medical Research Council
Funding Acknowledgements
C.K.F. and C.S.B. are supported by Australian NHMRC Leadership Investigator Grants (GNT1172900 and GNT1173361, respectively).