Changes in mental health symptoms from pre-COVID-19 to COVID-19 among participants with systemic sclerosis from four countries: A Scleroderma Patient-centered Intervention Network (SPIN) Cohort study
Brett D Thombs, Linda Kwakkenbos, Richard S Henry, Marie-Eve Carrier, Scott Patten, Sami Harb, Angelica Bourgeault, Lydia Tao, Susan J Bartlett, Luc Mouthon, John Varga, Andrea Benedetti, Catherine Fortune, Amy Gietzen, Genevieve Guillot, Nancy Lewis, Michelle Richard, Maureen Sauve, Joep Welling, Kim Fligelstone Show all
JOURNAL OF PSYCHOSOMATIC RESEARCH | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2020
INTRODUCTION: No studies have reported mental health symptom comparisons prior to and during COVID-19 in vulnerable medical populations. OBJECTIVE: To compare anxiety and depression symptoms among people with a pre-existing medical condition and factors associated with changes. METHODS: Pre-COVID-19 Scleroderma Patient-centered Intervention Network Cohort data were linked to COVID-19 data from April 2020. Multiple linear and logistic regression were used to assess factors associated with continuous change and ≥ 1 minimal clinically important difference (MCID) change for anxiety (PROMIS Anxiety 4a v1.0; MCID = 4.0) and depression (Patient Health Questionnaire-8; MCID = 3.0) symptoms, controll..View full abstract
The study was supported by funding from the Canadian Institutes of Health Research McGill University, the McGill Interdisciplinary Initiative in Infection and Immunity Emergency COVID-19 Research Fund; Scleroderma Canada, made possible by an educational grant for patient support programming from Boehringer Ingelheim; Scleroderma Society of Ontario; Scleroderma Manitoba; Scleroderma Atlantic; Scleroderma Australia; Scleroderma New South Wales; Scleroderma Victoria; Scleroderma Queensland; Scleroderma SASK; Scleroderma Association of BC; and Sclerodermie Quebec. Dr. Thombs was supported by a Tier 1 Canada Research Chair and a Fonds de recherche du Quebec -Sante (FRQ-S) researcher salary award, Dr. Benedetti was supported by a FRQ-S researcher salary award, Dr. Henry was supported by a Mitacs postdoctoral fellowship award, and Mr. Harb was supported by a CIHR Canada Graduate Scholarship-Master's award, all outside of the present work. No sponsor had any role in the study design; in the collection, analysis and interpretation of the data; in the writing of the report; or in the decision to submit the paper for publication.