The Accuracy of Diagnostic Testing in Determining Tree Nut Allergy: A Systematic Review
Tim Brettig, Thanh Dang, Vicki McWilliam, Rachel L Peters, Jennifer J Koplin, Kirsten P Perrett
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE | ELSEVIER | Published : 2021
BACKGROUND: Food allergy is most accurately diagnosed by a formal oral food challenge (OFC); however, it is time and labor intensive, risks the individual to severe reaction, and access is often a limiting step in the diagnostic process. This is compounded for tree nut allergy diagnosis as several OFCs may be required to determine allergy status to each individual tree nut. Accurate diagnosis using minimally invasive diagnostic tests in predicting clinical tree nut allergy is important to correctly identify those with potentially life-threatening reactions and to efficiently and safely tailor nut avoidance to only those nuts deemed allergic to enable less restricted diets and increased food ..View full abstract
T. Brettig is supported by a PhD Scholarship from the NHMRCfunded Centre for Food and Allergy Research (CFAR) .